Knowledge Center
Poster / Oct 13, 2021
Evaluation of the Relaxation State of Amorphous Itraconazole Using Solution Calorimetry
Source:
AAPS 2021
Track: Manufacturing and Analytical Characterization 鈥 Chemical
Monday, October 18, 2021 | 8:00 AM 鈥 9:00 AM ET
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Presenting Author:听Lu铆s Sousa听-听Senior Analytical Scientist, R&D Analytical Development
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Investigation of the relaxation phenomena in amorphous materials is key to understand and predict their physical stability. The work presented demonstrates the potential of solution calorimetry for monitoring changes in the relaxation state of amorphous materials. The advantage of this technique over traditional methods (XRPD) used for quantifying the amorphous/crystalline content is also demonstrated.
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