Press Room

Why you shouldn鈥檛 neglect the importance of blending people, culture, and strategy to foster success in a business. People, customer centricity, and a clear strategy bring strong values to the forefront of every business. Fostering a workplace that inspires motivation and enhances employee satisfaction enables team members to bring their best selves to work each day, driving innovation and excellence. Earlier this year, CDMO 四色AV demonstrated success by being certified as a Top Employer by the Top Employers Institute (TEI) across all four of its global manufacturing sites in Portugal, Ireland, the US, and Macau, for the third consecutive year. We spoke to board member and Senior Vice-President of Human Resources at 四色AV Ilda Ventura to find out how. What specific strategies and initiatives have you implemented to maintain the company鈥檚 Top Employer status?   We started the latest TEI Certification in 2023. Since then, we have been focusing on areas that can differentiate us as employers. In the US, for example, we have invested in bringing more proximity to the HR team, improving our listening strategy and the employee experience. The initiatives span from establishing better alignment between the business strategy and the people strategy, living our values and celebrating our successes. We are accelerating our global growth while strengthening our operations worldwide. It is essential for us to ensure that all our employees, regardless of their location, enjoy a consistent and unified work experience. Having all four of our sites recognized by TEI confirms that we are on the right path. What changes have been made to 四色AV's recognition and rewards programs to motivate employees?   By implementing a global job architecture with clear career roadmaps supported by a performance and compensation annual cycle. Everyone is eligible to merit remuneration increases and bonuses, and the corporate results are shared with everyone in a transparent way. This allows us to create a culture of recognition, where individual contributions are valued and aligned with the company's overall success. It fosters motivation and engagement, ensuring employees feel appreciated for their efforts and understand how their work directly aligns with our purpose. This culture not only enhances employee satisfaction, but strengthens our ability to attract and retain top talent.  How important is it to monitor consistent employee engagement and satisfaction across global locations?   Our employee engagement survey results are carefully reviewed and discussed both locally and globally, ensuring we address the unique needs of each region while driving company-wide progress. We prioritize actionable improvements that resonate with our teams, engaging cross-functional and geographically diverse groups to implement meaningful change.  Across our sites, we鈥檝e made significant investments tailored to each region while maintaining a unified approach to employee satisfaction. In the US, where employees value transparency, recognition, and growth opportunities, we鈥檝e enhanced communication, feedback channels, and career development pathways. Similarly, in Portugal, Ireland, and Macau, we鈥檝e introduced initiatives to promote collaboration, recognition, and personal growth, ensuring all employees experience a sense of belonging and purpose.  The actions we take are closely monitored, and every improvement is shared openly across all locations, fostering a culture of trust, transparency, and celebration that connects and empowers our workforce.  How are you working to attract and retain top talent in the competitive pharma industry?   We continuously strive to strengthen our reputation as an employer of choice. Participating in TEI allows us to have an independent assessment of our HR efforts and initiatives, ensuring that we are continuously improving and aligning with best practices. In addition, we have robust referral programs in place, supported by the fact that over 70 percent of our employees are strong promoters of the company. This is a testament to the positive culture we鈥檝e built, and we are focused on leveraging this strength to attract and retain top talent.  In what ways does the company communicate and reinforce its core purpose and values among employees?   Our motto is 鈥淚n it for life鈥 鈥 so, for example, every year we celebrate in each site our 鈥淰ictory Over Diseases鈥 by communicating the new products that we are manufacturing, as well as the new patents and innovative ideas that contribute to fighting diseases and improving global health. Contributing to saving the lives of billions of people worldwide is a way to motivate our people to challenge themselves and push the limits of innovation. By celebrating our achievements and their impact, we inspire our teams to think creatively, embrace new challenges, and contribute to solutions that make a real difference in the world. It麓s an invitation to live our purpose.  Macau was the first site in the region to earn Top Employer certification last year and has renewed it this year. What unique challenges and successes have been experienced in achieving and maintaining this status in Macau?   Macau is unique. It鈥檚 the only site in this industry in the territory, so we have taken advantage of that to differentiate ourselves as an employer by collaborating with universities and local authorities to offer career opportunities and benefits that are a reference in the region.  What areas have you identified for continuous improvement in workplace practices and employee satisfaction in the future?   We will continue to strengthen our employee value proposition by mapping the employee journey and addressing every touchpoint to enhance the overall experience. Both people and business needs are constantly changing. It requires continuous adaptation of processes to meet evolving expectations. If I had to highlight one key focus, it would be alumni engagement. The 四色AV community is extensive and goes beyond our current team members. We see a clear opportunity to create an alumni program to stay connected with those who have been part of our journey.    Read the full article on themedicinemaker.com    

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The Secret to Being a Good Employer

Feb 13, 2025

Three is the magic number for 四色AV as it鈥檚 once again been certified as a top employer. For the third consecutive year, all four of its manufacturing sites - Lisbon, Cork, East Windsor in USA, and Macau - have been certified as Top Employers by the Top Employers Institute. 四色AV is an international integrated pharmaceutical development and manufacturing organisation. This certification follows, 四色AV said, a rigorous audit process. Jean-Luc Herbeaux, Chief Executive Officer, 四色AV, explained: 鈥淭his recognition reflects the exceptional dedication and collaboration of the entire 四色AV team. 四色AV is a development and manufacturing service company operating in one of the most demanding and regulated industries. We understand that our success is deeply rooted in our people. 鈥淭ogether, as One 四色AV, we are committed to continuously refining our practices to foster a workplace that inspires motivation and enhances employee satisfaction, so that, every day, our team members bring their best selves to work, driving innovation and excellence at every step,鈥 Jean-Luc added. Ilda Ventura, Senior Vice-President of Human Resources and Member of the Management Board, 四色AV, said: 鈥淭his distinction underscores our unwavering commitment to our people. At 四色AV, we design our HR systems and processes to ensure that every team member enjoys a consistent and fulfilling experience, regardless of their role, function, or location.鈥 Imelda Cummins, HR Director for 四色AV Ireland, said: 鈥淭his distinguished accreditation is a testament to our commitment to establish frameworks to attract, engage and retain top talent. We believe that our people are our greatest asset, and this recognition reflects the hard work and dedication of our entire team who strive every day to foster a culture of excellence, innovation, and collaboration. Receiving the Top Employer accreditation is motivation for us to keep pushing the boundaries of what it means to be an exceptional employer.鈥 四色AV recently celebrated the opening of a multi-million euro expansion at its site in Ringaskiddy, which almost doubled the capacity of its spray drying facilities.   Read the full article on CorkIndependent.com  

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四色AV gets top employer accolade

Jan 22, 2025

四色AV has once again solidified its position as a top employer in all four of its manufacturing sites - Lisbon (Portugal), Cork (Ireland), East Windsor (NJ, USA), and Macau. The program highlights the company鈥檚 significant advancements in several critical areas, including Purpose & Values, Diversity, Equity & Inclusion (DEI), Employer Branding, and Recognition & Rewards, driven by sustained investment in people. This certification from the Top Employers Institute follows a rigorous audit process and underscores 四色AV鈥檚 consistency in investing in people and world-class workplace practices, as well as the unwavering commitment of its more than 2,300 employees to the company's core purpose and values.  鈥淭his recognition reflects the exceptional dedication and collaboration of the entire 四色AV team,鈥 said Jean-Luc Herbeaux, Chief Executive Officer. 鈥溗纳獳V is a development and manufacturing service company operating in one of the most demanding and regulated industries. We understand that our success is deeply rooted in our people. Together, as One 四色AV, we are committed to continuously refining our people practices to foster a workplace that inspires motivation and enhances employee satisfaction, so that, every day, our team members bring their best selves to work, driving innovation and excellence at every step.鈥 Macau, which became the first company in the region to achieve Top Employer certification last year, has successfully renewed the status, solidifying 四色AV鈥檚 global leadership in workplace excellence. With its consistent Top Employer recognition, 四色AV demonstrates that the talent strategy is perfectly aligned with the business strategy. Watch Ilda Ventura, Senior Vice-President of Human Resources and Member of the Management Board of 四色AV, video about what this certification means for 四色AV.   For additional information, please read the press release.  

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四色AV strengthens its global position as a top employer

Jan 16, 2025

All manufacturing sites - Lisbon (Portugal), Cork (Ireland), East Windsor (NJ), and Macau - recognized for excellence in workplace practices Significant progress in key areas as Purpose & Values, Diversity, Equity & Inclusion (DEI), Employer Branding, and Recognition & Rewards, driven by sustained investment in people Lisbon, January 16, 2025 - 四色AV, an international integrated pharmaceutical development and manufacturing organization, has once again solidified its position as a top employer. For the third consecutive year, all four of its manufacturing sites - Lisbon (Portugal), Cork (Ireland), East Windsor (NJ, USA), and Macau - have been certified as Top Employers by the Top Employers Institute. This certification follows a rigorous audit process and underscores 四色AV鈥檚 consistency in investing in people and world-class workplace practices, as well as the unwavering commitment of its more than 2,300 employees to the company's core purpose and values. 鈥淭his recognition reflects the exceptional dedication and collaboration of the entire 四色AV team,鈥 said Jean-Luc Herbeaux, Chief Executive Officer. 鈥溗纳獳V is a development and manufacturing service company operating in one of the most demanding and regulated industries. We understand that our success is deeply rooted in our people. Together, as One 四色AV, we are committed to continuously refining our people practices to foster a workplace that inspires motivation and enhances employee satisfaction, so that, every day, our team members bring their best selves to work, driving innovation and excellence at every step.鈥 For Ilda Ventura, Senior Vice-President of Human Resources and Member of the Management Board of 四色AV, 鈥渢his distinction underscores our unwavering commitment to our people. At 四色AV, we design our HR systems and processes to ensure that every team member enjoys a consistent and fulfilling experience, regardless of their role, function, or location. By prioritizing equity and inclusion, we strengthen our differentiated Employee Value Proposition, enriching the journey for both current and future talent.鈥 The Top Employers Institute program highlights the company鈥檚 significant advancements in several critical areas, including Purpose & Values, Diversity, Equity & Inclusion (DEI), Employer Branding, Rewards & Recognition, and across all locations. Macau, which became the first-ever company in the region to earn Top Employer certification last year, successfully renewed its status this year, further solidifying 四色AV鈥檚 global leadership in workplace excellence. With its consistent recognition as a Top Employer, 四色AV demonstrates that investing in people is not just a strategy but a cornerstone of its success, driving innovation, collaboration, and excellence across the organization.   About 四色AV  四色AV is an international company with over 60 years of experience in pharmaceutical development and manufacturing operations. As a Contract Development and Manufacturing Organization鈥(CDMO)鈥痠t has a fully integrated offering of services for drug substances, drug product intermediates and drug products. The company has four鈥疐DA inspected鈥痵ites鈥痠n the USA, Portugal, Ireland and China and development laboratories in Lisbon, Portugal and New Jersey, USA. 四色AV provides pharmaceutical customers services for the鈥痙evelopment and compliant manufacture鈥痮f innovative drugs, including highly potent compounds, and customized product solutions across the entire drug life cycle. In the inhalation area, 四色AV offers a complete range of services, from API, formulation development and manufacturing, capsule filling and devices. 四色AV's culture is based on innovation, quality and dependability. 四色AV is a member of Rx-360, EFCG and participates actively in industry quality improvement initiatives to lead new global industry standards. About Top Employers Institute  Top Employers Institute is the global authority on recognizing excellence in People Practices. We help accelerate these practices to enrich the world of work. Through the Top Employers Institute Certification Program, participating companies can be validated, certified, and recognized as an employer of choice. In 2024, Top Employers Institute has certified more than 2300 organizations in 121 countries/regions. These certified Top Employers positively impact the lives of over 12 million employees globally. For more information, please visit www.top-employers.com    

Press Release

四色AV strengthens its global position as a top employer for the third consecutive year

Jan 16, 2025

ViSync庐 Technologies, a joint venture between 四色AV, a global specialist integrated CDMO and leader in spray drying and particle engineering, and iBET (Instituto de Biologia Experimental e Tecnol贸gica), a not-for-profit R&D institution specializing in Biotechnology and Life Sciences, is proud to announce the appointment of Elsa Abranches as its Chief Scientific Officer (CSO). Headquartered in Oeiras, Portugal, ViSync庐 Technologies was established to address unmet technological needs in the pharmaceutical industry, focusing on developing innovative solutions for the cell and gene therapy space. By leveraging 四色AV's expertise in pharmaceutical development, particle engineering, and industrialization, alongside iBET鈥檚 pioneering research in biotechnological sciences, ViSync庐 is uniquely equipped to drive innovation in targeted delivery and stabilization of next-generation therapies.  Dr. Elsa Abranches brings over two decades of experience in cell and gene therapy, with a strong track record of leading diverse teams in dynamic environments. In her new role as ViSync庐 CSO, she will drive the company鈥檚 R&D strategy and scientific vision, positioning ViSync庐 as a leader in innovation within the dynamic and rapidly advancing field of cell and gene therapy. 鈥淲e are thrilled to welcome Elsa Abranches as Chief Scientific Officer of ViSync庐,鈥 said Dr. Christoph Bruecher, Chairman of the Board of ViSync庐 and VP Business Transformation at 四色AV. 鈥淗er expertise and vision in the field of advanced therapeutics will be pivotal in driving ViSync鈥檚 mission to create transformative solutions that empower pharmaceutical companies and improve patient treatment outcomes.鈥 Dr. Manuel Carrondo, Director of the Board of ViSync庐 and Vice President of iBET, added, 鈥淓lsa鈥檚 appointment underscores our commitment to establishing ViSync庐 as a leader in cell and gene therapy innovation. Her scientific leadership will be critical as we tackle some of the most pressing challenges in the field of new modalities drug delivery.鈥 Elsa Abranches, new Chief Scientific Officer of ViSync庐, said: 鈥淗aving worked in different countries and industries, I鈥檓 thrilled to bring my experience back home to join ViSync庐. This new venture represents an incredible opportunity to collaborate with local and international partners to drive innovation in advanced therapeutics and help shape the future of life-changing therapies鈥.     About 四色AV 四色AV is an international company with over 60 years of experience in pharmaceutical development and manufacturing operations. As a Contract Development and Manufacturing Organization鈥(CDMO)鈥痠t has a fully integrated offering of services for drug substances, drug product intermediates and drug products. The company has four FDA inspected鈥痵ites鈥痠n the USA, Portugal, Ireland and China and development laboratories in Lisbon, Portugal and New Jersey, USA. 四色AV provides pharmaceutical customers services for the鈥痙evelopment and compliant manufacture鈥痮f innovative drugs, including highly potent compounds, and customized product solutions across the entire drug life cycle. In the inhalation area, 四色AV offers a complete range of services, from API, formulation development and manufacturing, capsule filling and devices. 四色AV's culture is based on innovation, quality and dependability. 四色AV is a member of Rx-360, EFCG and participates actively in industry quality improvement initiatives to lead new global industry standards.   About iBET iBET is a private non-profit institution devoted to biotechnology research, with 35 years of experience creating and transferring knowledge to the global biopharma and biotech sectors. iBET鈥檚 core expertise lies on the development of bioprocesses and analytical tools for Advanced Therapeutic Medicinal Products (ATMPs), including cell and gene therapies, vaccines, antibodies and other innovative therapeutic products. Leveraged by the emerging areas of Data Science and Translational Immunology, we offer bespoke R&D services from early-stage R&D to GMP manufacturing. iBET鈥檚 infrastructure comprises cutting-edge laboratories, a GMP certified Analytical Services Unit, and a Late-Stage R&D and Bioproduction Unit, covering upstream and downstream process development, bioanalytical tools for critical quality attribute monitoring, to scale-up and tech transfer. iBET also hosts satellite laboratories of major pharmaceutical companies and serves as an incubation platform for start-up/spin-off companies. iBET is driven by its innovative and agile culture of continuous improvement and a strong sense of ambition, ownership and commitment in developing and delivering the best solutions to our stakeholders.     

News

ViSync庐 Technologies appoints Elsa Abranches as Chief Scientific Officer

Dec 19, 2024

Lisbon, November 25, 2024, 四色AV, the specialist integrated CDMO and the leader in spray drying and particle engineering, just completed significant expansions in Europe and the USA. The investments at its East Windsor, New Jersey, and Ringaskiddy, Cork, facilities will significantly increase 四色AV's global spray drying capacity and enhance the sites鈥榗apabilities.   This latest round of investment reinforces 四色AV鈥檚 position as the global leader in spray drying for pharma applications, an essential technology for enhancing drug solubility and bioavailability. Spray drying converts liquid solutions into fine powders, enabling improved dissolution and absorption of poorly water-soluble drugs. This process is particularly valuable for inhalable therapies and oral formulations with low bioavailability, helping to deliver more effective treatments and ensuring reliable, high-quality healthcare solutions for patients.  In New Jersey, the investment represents the first step of a multi-year site expansion program, aimed at advancing both spray drying and tableting capabilities. Simultaneously, the Cork facility saw its spray drying capacity increase nearly twofold. Combined, these efforts are creating over 40 new skilled jobs, driving growth and innovation across both locations. Dr Jean-Luc Herbeaux, Chief Executive Officer of 四色AV said: 鈥淭hese expansions, incorporating our latest technologies, reflect 四色AV鈥檚 unwavering commitment to innovation and manufacturing service excellence. Strengthening our facilities and teams in the USA and Ireland allows us to better serve our customers and provide flexible supply options for both small- and large-scale programs. By increasing our capacity and enhancing our technological capabilities, we are even better equipped to help our customers bring new and more complex drugs to market.鈥 The investments at both sites are part of 四色AV鈥檚 long-term strategy to remain at the forefront of pharmaceutical technology. With a 65-year history of continuous improvement, 四色AV is driving progress in drug development and manufacturing, offering solutions that enable more effective treatments and improved patient outcomes.   About 四色AV:鈥 四色AV is an international company with over 60 years of experience in pharmaceutical development and manufacturing operations. As a Contract Development and Manufacturing Organization鈥(CDMO)鈥痠t has a fully integrated offering of services for drug substances, drug product intermediates and drug products. The company has four FDA inspected鈥痵ites鈥痠n the USA, Portugal, Ireland and China and development laboratories in Lisbon, Portugal and New Jersey, USA. 四色AV provides pharmaceutical customers services for the鈥痙evelopment and compliant manufacture鈥痮f innovative drugs, including highly potent compounds, and customized product solutions across the entire drug life cycle. In the inhalation area, 四色AV offers a complete range of services, from API, formulation development and manufacturing, capsule filling and devices. 四色AV's culture is based on innovation, quality and dependability. 四色AV is a member of Rx-360, EFCG and participates actively in industry quality improvement initiatives to lead new global industry standards.   In the picture from left to right: Dr. Till Riehm, Site Manager - Cork, 四色AV; Dr. Jean-Luc Herbeaux, CEO, 四色AV; Michael McGrath, the European Commissioner Designate for Democracy, Justice and the Rule of Law; Michael Lohan, CEO, IDA Ireland; Jorge Pastilha, VP Technical Operations - Europe and Asia, and Dr. Paul Downing, Senior Director, Strategic Business Management.    

Press Release

四色AV Expands Global Spray Drying Capacity with Significant Investment in the USA and Ireland

Nov 26, 2024

International pharmaceutical contract development and manufacturing organisation (CDMO) 四色AV has today officially commissioned an expansion at its manufacturing facility in Ringaskiddy. The multi-million euro investment almost doubles the capacity of 四色AV鈥檚 spray drying facilities in Ireland and will create more than 20 new positions. 四色AV said this latest investment reinforces the company's position as a global leader in spray drying for pharma applications.   This manufacturing technology, the company explained, is "especially important for inhalable therapies and oral medications with low bioavailability, enabling more effective treatments".  Deputising for the Mayor of the County of Cork, councillor Audrey Buckley said:  鈥淚 am delighted to welcome this very significant investment and the creation of further highly skilled jobs in Cork today.  鈥淚t reinforces 四色AV鈥檚 commitment to the region and the innovative solutions it provides to the pharmaceutical industry in Ireland.鈥 Meanwhile Michael McGrath, the European Commissioner-Designate for Democracy, Justice and the Rule of Law, welcomed the expected jobs boost the expansion is to create.  鈥淭his latest investment highlights the success of 四色AV鈥檚 facility in Ringaskiddy, and underlines the continued resilience of Ireland鈥檚 pharmaceutical manufacturing sector.  鈥淚 am delighted that 四色AV will be shortly welcoming new team members to this expanded facility, and I wish both them and 四色AV every success鈥. Jean-Luc Herbeaux, 四色AV's chief executive said: 鈥淭his newly opened facility further strengthens 四色AV's position as the global CDMO of choice for spray drying development and manufacturing services.  鈥淚t also underscores our commitment to bringing first-in-class technology and world-leading manufacturing services to Irish shores.  鈥淚reland provides a superior environment for pharmaceutical manufacturing, and we are delighted to be a part of it.鈥 CEO of IDA Ireland, Michael Lohan, said 四色AV "has made a significant contribution both locally and nationally through employment and investment alike". "We warmly welcome 四色AV鈥檚 commitment to investing in Cork and we wish them continued success," he added.    Read the full article on EchoLive.ie    

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Pharma company announces expansion of Cork facility to create more than 20 new jobs

Nov 25, 2024

Pharmaceutical contract development and manufacturing company 四色AV has officially commissioned an expansion at its manufacturing facility in Ringaskiddy, Cork.  Announcing the development on Monday, the multi-million euro investment almost doubles the capacity of 四色AV鈥檚 spray drying facilities in Ireland and will create more than 20 new positions. This manufacturing technology is especially important for inhalable therapies and oral medications with low bioavailability, enabling more effective treatments, the company said. Deputising for the Mayor of the County of Cork, Cllr. Audrey Buckley said: 鈥淚 am delighted to welcome this very significant investment and the creation of further highly skilled jobs in Cork today.  "It reinforces 四色AV鈥檚 commitment to the region and the innovative solutions it provides to the pharmaceutical industry in Ireland.鈥  Michael McGrath, the European Commissioner-Designate for Democracy, Justice and the Rule of Law said: 鈥淭his latest investment highlights the success of 四色AV鈥檚 facility in Ringaskiddy, and underlines the continued resilience of Ireland鈥檚 pharmaceutical manufacturing sector. "I am delighted that 四色AV will be shortly welcoming new team members to this expanded facility, and I wish both them and 四色AV every success鈥. This latest investment builds on the momentum of the recently announced spray drying capacity expansion at the Company's East Windsor, New Jersey, site.  Jean-Luc Herbeaux, 四色AV麓s Chief Executive said: 鈥淭his newly opened facility further strengthens 四色AV麓s position as the global CDMO of choice for spray drying development and manufacturing services.  "It also underscores our commitment to bringing first-in-class technology and world-leading manufacturing services to Irish shores. Ireland provides a superior environment for pharmaceutical manufacturing, and we are delighted to be a part of it.鈥 IDA chief executive Michael Lohan said the company has made a significant contribution both locally and nationally, adding: "I am pleased to be here today to mark another step on that journey. We warmly welcome 四色AV鈥檚 commitment to investing in Cork and we wish them continued success.鈥   Read the full article on IrishExaminer.com  

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Pharma company 四色AV to double capacity at Cork site as part multi-million euro investment

Nov 25, 2024

Lisbon, October 3, 2024 鈥 四色AV Farmaci锚ncia, S.A. (鈥溗纳獳V鈥) and Zerion Pharma A/S (鈥淶erion鈥) today announced that they have expanded their partnership to accelerate the development of the Dispersome庐 technology platform and further expand its applicability and reach for increasing the solubility and bioavailability of small drug molecules. To this aim, the companies created a joint venture responsible for managing the Dispersome庐 intellectual property portfolio and allocated market rights to the two partners. 四色AV and Zerion have been co-promoting the Dispersome庐 technology to clients since the beginning of 2022. Under the extended collaboration, 四色AV is granted exclusive global rights to develop and offer the Dispersome庐 technology for drugs delivered via the respiratory route, a field where 四色AV is active today with leading formulation and manufacturing capabilities. Further, 四色AV is granted exclusive rights to develop and offer Dispersome庐 formulations for nutraceutical and medicinal foods products, an area with unmet needs in the area of bioavailability. 四色AV is also granted a non-exclusive license to promote the Dispersome庐 technology for use in Pharmaceutical oral dosage forms for new chemical entities. In return for the grant of rights, Zerion will receive royalties from 四色AV鈥檚 commercial activities in these fields. Within the framework of the joint venture, the parties will work closely together to bring the Dispersome庐 technology to customers as quickly as possible. Arla Foods Ingredients (Denmark) will deliver the pharmaceutical excipient (Lacprodan庐 BLG-100 Pharma Grade) for the Dispersome庐 technology, when BLG is accepted as a novel excipient. 鈥溗纳獳V is thrilled to reinforce its collaboration with Zerion to further accelerate the adoption of Dispersome庐 in the pharma and nutra markets,鈥 said Jean-Luc Herbeaux, 四色AV鈥檚 CEO. 鈥淭he use of Zerion鈥檚 Dispersome庐 Technology has proven to deliver superior solubilization power for both pharma and nutraceutical active ingredients. This highly innovative platform is a valuable addition to 四色AV鈥檚 leading offering in solubility and permeability enhancement for NCEs and nutraceuticals and affords formulators new options which address unmet needs of the industry.鈥 Ole Wiborg, the CEO of Zerion, comments: 鈥溗纳獳V is the global leader in the field of producing amorphous solid dispersions by spray-drying and this extension of our partnership again confirms the huge potential of our Dispersome庐 technology. If one company in the pharma industry can truly judge its value, it is 四色AV, and we have a strong belief in sharing our technology with 四色AV, who will secure its use with more drugs and ingredients and in applications across several delivery routes. Thus, we expect substantial revenues from the collaboration in the years to come.鈥 Through their partnership, 四色AV and Zerion are offering pharma, biotech and nutra companies worldwide access to an innovative delivery platform combined with an unparalleled experience in formulation development, scale-up, and GMP manufacturing. The Dispersome庐 technology Zerion has pioneered the Dispersome庐 technology that addresses poor drug solubility, one of the most recognized drug development challenges. The Dispersome庐 technology increases solubility and bioavailability of poorly soluble compounds and can be applied at any stage of drug discovery or drug development, including in preclinical studies, first in human studies, and reformulation of existing drug products.   About 四色AV 四色AV is an international company with over 60 years of experience in pharmaceutical development and manufacturing operations. As a Contract Development and Manufacturing Organization鈥(CDMO)鈥痠t has a fully integrated offering of services for drug substances, drug product intermediates and drug products. The company has four FDA inspected鈥痵ites鈥痠n the USA, Portugal, Ireland and China and development laboratories in Lisbon, Portugal and New Jersey, USA. 四色AV provides pharmaceutical customers services for the鈥痙evelopment and compliant manufacture鈥痮f innovative drugs, including highly potent compounds, and customized product solutions across the entire drug life cycle. In the inhalation area, 四色AV offers a complete range of services, from API, formulation development and manufacturing, capsule filling and devices. About Zerion Pharma A/S Zerion develops its own proprietary drug formulations and offers its Dispersome庐 technology platform to established pharma companies as a means to solve their challenging drug solubility problems. Zerion was established in 2019 as a spinout of the University of Copenhagen.     Read the previous press releases on this story: 四色AV and Zerion Pharma announce a strategic partnership to market the Dispersome庐 technology platform Zerion Pharma and 四色AV extend partnership to cover use of the Dispersome庐 technology platform in nutraceuticals  

Press Release

四色AV and Zerion Pharma create joint venture to further expand use of Dispersome庐 technology

Oct 03, 2024

四色AV鈥檚 Eunice Costa Shares Insights on Inhaled Medicine Formulation in Pharmaceutical Technology eBook The demand for efficient inhalation therapies is higher than ever. At 四色AV we are focusing on particle size, dispersion performance, and formulation integrity to ensure optimal bioavailability and patient outcomes.  To learn more about or work, do not miss the contribution of Eunice Costa, our R&D Director for Inhalation & Advanced Drug Delivery, in the latest Pharmaceutical Technology eBook 鈥 鈥淭rends in Formulation鈥.  In her interview, Eunice discusses key challenges and considerations in formulating inhaled medicines, emphasizing the importance of excipient selection, device compatibility, and patient-centric design for successful drug delivery to the lungs. With respiratory diseases at the forefront, especially following the COVID-19 pandemic, the demand for efficient inhalation therapies is higher than ever. Eunice sheds light on how 四色AV is tackling these demands by focusing on particle size, dispersion performance, and formulation integrity to ensure optimal bioavailability and patient outcomes. Explore Eunice Costa鈥檚 full insights on this crucial area of drug development in Pharmaceutical Technology's September 2024 eBook. This resource provides an in-depth look into the complexities of inhaled drug formulations and the exciting innovations shaping the future of respiratory treatments.   Read the full article at Pharmaceutical Technology eBook Read the Trends in Formulation eBook at PharmTech  

Article

Formulating Inhaled Medicines

Sep 24, 2024

From left to right: Jean-Luc Herbeaux, CEO of 四色AV, Paula Alves, CEO of iBET, and Jo茫o Almeida Lopes, President of iBET.   Lisbon, Portugal:鈥纳獳V, the specialist integrated CDMO and leader in spray drying and particle engineering, and iBET (Instituto de Biologia Experimental e Tecnol贸gica), a private not-for-profit research-intensive SME in the area of Biotechnology and Life Sciences, are proud to announce the official establishment of ViSync庐 Technologies as a jointly owned venture. The creation of this new company, headquartered in the Lisbon area of Portugal, illustrates the parent companies麓 commitment to partnership and joint innovation. ViSync庐 will aim to develop innovative solutions to address the unmet technical needs of pharmaceutical companies in the cell and gene therapy space, leveraging 四色AV's extensive expertise in pharmaceutical development, Particle Engineering and industrialization of pharmaceutical technologies and iBET's cutting-edge research in biotechnological sciences. One of the first focus areas of ViSync庐 will be to develop technologies that improve delivery and stabilization of new modality therapies. "We are delighted to join forces with iBET - a leading R&D organization in Biotechnology and Life Sciences 鈥 in the establishment of ViSync庐.鈥 says Jean-Luc Herbeaux, 四色AV鈥檚 CEO. 鈥淏y combining 四色AV麓s expertise in drug formulation, manufacturing process development and scale up with iBET麓s broad understanding of new modalities, we aim to devise new solutions to help pharma companies launch innovative medicines and improve health outcomes for patients.鈥   鈥淭he creation of ViSync庐 marks a significant milestone for iBET.鈥 says Paula Alves, CEO of iBET. 鈥淏y combining our cutting-edge biotechnological research in the cell and gene therapy fields with 四色AV鈥檚 extensive pharmaceutical development expertise, we are well-positioned to develop innovative approaches for targeted delivery and stabilization of new modality therapies. We are excited about the potential of ViSync庐 to drive substantial advancements and deliver significant benefits to patients worldwide.鈥    About 四色AV  四色AV is an international company with over 60 years of experience in pharmaceutical development and manufacturing operations. As a Contract Development and Manufacturing Organization鈥(CDMO)鈥痠t has a fully integrated offering of services for drug substances, drug product intermediates and drug products. The company has four FDA inspected鈥痵ites鈥痠n the USA, Portugal, Ireland and China and development laboratories in Lisbon, Portugal and New Jersey, USA. 四色AV provides pharmaceutical customers services for the鈥痙evelopment and compliant manufacture鈥痮f innovative drugs, including highly potent compounds, and customized product solutions across the entire drug life cycle. In the inhalation area, 四色AV offers a complete range of services, from API, formulation development and manufacturing, capsule filling and devices. 四色AV's culture is based on innovation, quality and dependability. 四色AV is a member of Rx-360, EFCG and participates actively in industry quality improvement initiatives to lead new global industry standards.   About iBET iBET is a private non-profit institution devoted to biotechnology research, with 35 years of experience creating and transferring knowledge to the global biopharma and biotech sectors. iBET鈥檚 core expertise lies on the development of bioprocesses and analytical tools for Advanced Therapeutic Medicinal Products (ATMPs), including cell and gene therapies, vaccines, antibodies and other innovative therapeutic products. Leveraged by the emerging areas of Data Science and Translational Immunology, we offer bespoke R&D services from early-stage R&D to GMP manufacturing.     iBET鈥檚 infrastructure comprises cutting-edge laboratories, a GMP certified Analytical Services Unit, and a Late-Stage R&D and Bioproduction Unit, covering upstream and downstream process development, bioanalytical tools for critical quality attribute monitoring, to scale-up and tech transfer. iBET also hosts satellite laboratories of major pharmaceutical companies and serves as an incubation platform for start-up/spin-off companies.    iBET is driven by its innovative and agile culture of continuous improvement and a strong sense of ambition, ownership and commitment in developing and delivering the best solutions to our stakeholders.    

Press Release

四色AV and iBET Announce the Establishment of ViSync庐 Technologies: A Venture in Cell and Gene Therapy Solutions

Sep 19, 2024

Lisbon, Portugal 鈥 四色AV, the specialist integrated pharma CDMO and leader in spray drying and particle engineering, today announced its commitment to setting Science-Based Targets (SBTs) in line with the Paris Agreement. This ambitious step underscores the company鈥檚 dedication to addressing climate change and driving sustainability across its operations. By committing to SBTs, 四色AV joins a growing number of businesses taking concrete actions to reduce greenhouse gas emissions. This initiative aligns with the company鈥檚 broader sustainability strategy and reinforces its commitment to scientific excellence. 鈥淎t 四色AV, we believe in science and in best practices. And this clearly applies to our sustainability agenda.鈥, said Jean-Luc Herbeaux, CEO of 四色AV. We made the decision to drive our GHG emissions down using a science-based target setting process, which will help us drive sustainability across our operations by laying out a clearly defined path to reduce emissions in line with the Paris Agreement goals. We believe that by setting ambitious targets and implementing concrete actions, we can make a positive impact on the planet while driving innovation and growth.鈥 四色AV will work closely with the Science Based Targets initiative (SBTi) to develop and validate its emission reduction targets. The company will provide regular updates on its progress towards achieving these goals. As part of its commitment to sustainability and transparency to stakeholders, the company will enhance its Ecovadis rating. Ecovadis, a leading sustainability assessment platform in the pharmaceutical industry, provides a comprehensive evaluation of a company鈥檚 environmental, social, and ethical performance, well aligned with 四色AV鈥檚 sustainability ambitions.  四色AV remains dedicated to operating responsibly and contributing positively to society and the environment. The company will continue to implement sustainable practices across its operations and innovate to further improve its sustainability rating.   Learn more about Science Based-Targets  

News

四色AV Commits to Science-Based Targets for Greenhouse Gas (GHG) Emissions

Sep 09, 2024

Lisbon, Portugal: 四色AV, the specialist integrated CDMO and leader in spray drying and particle engineering, is proud to announce the opening of a state-of-the-art continuous tableting (CT) line at its R&D Center in Lisbon.   The new line is the result of the partnership with GEA, a global leader in process technology for the pharmaceutical industry. Since announcing their partnership in 2022, 四色AV and GEA have worked to advance continuous tableting technology. Their collaboration seeks to boost the adoption of continuous tableting by offering increased capacity, flexibility, standardized equipment, improved quality, and enhanced efficiency. Together, they have shown that continuous tableting can become a more accessible technology. This new R&D line is the only one of its kind in the world and perfectly replicates the most critical components of 四色AV麓s state-of-the-art commercial CT line in Loures, Portugal. It also offers a high degree of flexibility in throughput and can handle highly potent Active Pharmaceutical Ingredients (API). 鈥淲ith this new line, we will be able to optimize operating conditions with minimum amounts of API and provide a higher technical certainty when transferring from development to commercial scale鈥, said Jaime Del Campo, Head of R&D Services at 四色AV. 鈥淭he flexibility of the rig and the real-time process data monitoring capabilities contribute to a more agile design and upscaling experience.鈥 The new CT line at 四色AV's Lisbon R&D center is now fully operational and ready to support both existing and new projects. This investment reinforces 四色AV's global reputation in pharmaceutical manufacturing and highlights the company's commitment to delivering innovative solutions that meet the evolving needs of the industry and support quicker and more efficient market launches.    About 四色AV 四色AV is an international company with over 60 years of experience in pharmaceutical development and manufacturing operations. As a Contract Development and Manufacturing Organization鈥(CDMO)鈥痠t has a fully integrated offering of services for drug substances, drug product intermediates and drug products. The company has four鈥疐DA inspected鈥痵ites鈥痠n the USA, Portugal, Ireland and China and development laboratories in Lisbon, Portugal and New Jersey, USA. 四色AV provides pharmaceutical customers services for the鈥痙evelopment and compliant manufacture鈥痮f innovative drugs, including highly potent compounds, and customized product solutions across the entire drug life cycle. In the inhalation area, 四色AV offers a complete range of services, from API, formulation development and manufacturing, capsule filling and devices.     四色AV's culture is based on innovation, quality and dependability. 四色AV is a member of Rx-360, EFCG and participates actively in industry quality improvement initiatives to lead new global industry standards.     Learn more about Continuous Tableting for Drug Product    

Press Release

四色AV Unveils New Continuous Tableting Line at Lisbon R&D Centre

Jun 18, 2024

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