Knowledge Center
Patent / Aug 18, 2016
New polymorphic forms of minocycline base and process for their preparation
Source:
WO 2016128760
The present invention concerns new forms of crystalline minocycline base. In particular, two new crystalline polymorphic forms, designated Form IV and Form V of minocycline base are provided. These are characterized by XRD, FTIR and TGA. Processes for preparing the new polymorphic forms and their use in pharmaceutical compositions are also provided. Form IV and form V are prepared by dissolving and/or suspending minocycline base in an organic solvent followed by crystallization.
Also in the Knowledge Center
/ Jan 01, 1973
21-Sulfuric acid or 21-orthophosphoric acid ester sodium salts of prednisolone or 9.alpha.-fluoro-16.beta.-methylprednisolone
Read more
Scientific Article
Scientific Article
/ Jan 01, 2011
Method for monofluoromethylation of organic substrates to prepare biologically active organic compounds
Read more
Scientific Article