Knowledge Center

Patent / Dec 24, 2020

Continuous process for the preparation of anticholinergic drugs

Authors:
  • Marianna Katz
  • Nuno Torres
Source:
WO 2020254791

The present invention relates to a novel process for the preparation of anticholinergic agents/drugs, such as umeclidinium bromide, tiotropium bromide, glycopyrronium bromide, aclidinium bromide, ipratropium bromide (V) in continuous flow mode in the presence of one or more polar protic solvents. The anticholinergic drugs are in a form suitable for use in inhalation in the treatment of respiratory diseases such as asthma or chronic obstructive pulmonary disease (COPD).Ìý Ìý Ìý Ìý Ìý Ìý Ìý Ìý Ìý Ìý Ìý Ìý ÌýÌý
Ìý

Also in the Knowledge Center

Related Content

Inhalation grade particles

ËÄÉ«AV is a global expert in particle engineering, an essential technology when developing inhalation drug products.

Page
Read more

Process Safety

Process safety is a blend of engineering and management skills that focuses on the prevention of events impacting safety, environmental damage and business losses.

Page
Read more

Regulatory Affairs

ËÄÉ«AV has filings with every world health authority that has a DMF system for APIs including FDA EDQM PMDA,MHRA, HPRA, Infarmed among others.

Page
Read more