Drug Substance Technologies
We constantly innovate to find better, more efficient ways of doing things.
As new chemical entities have become increasingly complex over the years, ËÄÉ«AV recognized the need to look beyond the chemistry knowledge and experience of its scientific teamÌýto embrace the use of specializedÌýequipment, ensuring precise process controlÌýunder the mostÌýstringent process conditions.
In addition, we have developed considerable expertise with innovative technologies, such as membrane purification, as well as the scale-up of chromatographic purifications, all the way to industrial scale, enabling us to tackle even the most challenging purifications.
No less important, is the ability of our scientists to understand the key factorsÌýthat ensureÌýsuccessful scale-up against tight development timelines. ToÌýguarantee robustness of operation of your processes at scale, ËÄÉ«AV has developed innovative Process Modeling techniques and Scale Down equipment to model, understand and refine the engineering of industrial scale manufacturing in a controlled laboratory environment.Ìý
Ìý
Ìý
PRIME -ÌýA Knowledge-based Assessment Tool to Classify Pharmaceutical Processes
The manufacturing of API is a long and complex process. The comparison between the different processes is not easy since the chemical structures vary and therefore the compounds' physical properties also change.
PRIME is a tool we developed which is able to take advantage ofÌý60 years of experience in developing API process.ÌýThe use of this tool allows us to develop our clients’ projects to better manage the expectations at different lifecycle stages of the processes.
Ìý
Interested?
Ìý Watch our On-Demand WebinarÌýwhere our speakers share their views on this new tool that is able to accelerate the development process. Recorded on May 11th, 2020 Ìý |
Ìý Ìý PRIME wins theÌý16th CPhI Pharma AwardsÌý |
Ìý
Isolation of a complex API
Successful integration of Chromatography, Nanofiltration and Spray Drying.