Knowledge Center
Patent / Jan 01, 1972
9-Fluoro-16.beta.-methyl steroids
Source:
US 3792046
The title compds. (I) were prepd. from pregnatriene (II) by treatment with MeCONHBr and aq. HClO4 to give the 9.alpha.-bromo-11.beta.-hydroxy deriv., treatment with NaOH to give the 9,11-epoxy deriv. which was treated with aq. HF to give I (R = H) which could be treated with I-MeOH in the presence of CaO to give the 21-diiodo deriv. which was treated with KOAc, giving I (R = OAc).
Also in the Knowledge Center
Scientific Article
/ Jan 01, 1996
Preparation, crystal structure and mechanism of formation of a novel dinuclear carbopentazane complex, [Rh2(PPh3)4{(NH2NH)2CH2}][NO3]2
Read more
Scientific Article
Scientific Article