Knowledge Center
Article / Jan 01, 1984
New nitrogen-containing rhodium catalysts
Source:
Actas Simp. Iberoam. Catal., 9th (1984), Volume 1, 446-52
The reaction of (Ph3P)3RhCl with MeNHNHMe.2HCl, in an inert atm., produced the N-contg. Rh complex Ph3PRhCl4NHMeNHMe (I). The use of I in the homogeneous hydrogenation of the exocyclic methylene group of methacycline-HCl allowed virtually asym. synthesis of the required clin. active enantiomer of doxocycline. Further, the amt. of Rh necessary for the complete hydrogenation was considerably less than the amts. indicated in the literature.
Also in the Knowledge Center
/ Dec 18, 2020
Rheological characterization of polymeric solutions used in spray drying process
Read more
Scientific Article
/ Nov 30, 2020
Semi-Automation in Inhaler Testing - Exploring the Potential & Practicalities
Read more
Scientific Article
/ Oct 23, 2020
Technical advances towards the industrial application of transaminases for the synthesis of chiral amines
Read more
Scientific Article