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Presentation / Oct 17, 2021

Understanding Dry Powder Inhalers Formulations: Role of Surface Polarity of lactose mixtures

Authors:
  • Ricardo Gonçalves
Source:
AAPS 2021

Track: Formulation and Delivery – Chemical
Rapid Fire: Role of Excipients in Formulation & Drug Product Development (CE)

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Ricardo Gonçalves R&D Analytical Development | ËÄÉ«AV

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Presenting Author:ÌýRicardo GonçalvesÌý-ÌýAnalytical Scientist, R&D Analytical Development

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Why do we use small lactose particles to improve Dry Powder Inhaler formulations? Why sieved and milled lactose particles present different properties? This presentation explores the role of surface energetics, measured using inverse gas chromatography, in the behavior of DPI formulations and the implication on their aerodynamic performance.

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