Knowledge Center

Poster / Oct 18, 2021

Spray-Dried Composite Formulation Containing DSPC for Lung Sustained Release

Authors:
  • Beatriz Noriega Fernandes
Source:
AAPS 2021

Track: Formulation and Delivery – Chemical
Monday, October 18, 2021 | 12:30 PM – 1:30 PM ETÌý

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Beatriz Noriega-Fernandes Inhalation and Advanced Drug Delivery R&D | ËÄÉ«AV

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Presenting Author:ÌýBeatriz Noriega-FernandesÌý-ÌýScientist, Inhalation and Advanced Drug Delivery Group, R&D

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Although drug delivery to the lung presents several advantages, its therapeutic efficiency is limited by a rapid clearance. Thus, this poster presentation will focus on the development of sustained release formulations suitable for lung delivery.Ìý The main goal will be to assess the impact of encapsulating a model drug (fluticasone propionate, FP) in 1,2-distearoyl-sn-glycero-3-phosphocholine (DSPC) vesicles prior to spray-drying (SD) on the final product aerodynamic performance and dissolution.

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