Knowledge Center
Poster / Nov 12, 2017
Optimizing Disintegration in Tablets of Amorphous Solid Dispersions
Source:
AAPS 2017
Good bioavailability of amorphous solid dispersions (ASDs) not only depends on dissolution rate/extent but also on the capability to inhibit/avoid crystallization, ensuring that supersaturated state is retained to promote absorption. Here, the type and amount of carrier polymer used in ADSs preparation have a strong impact on the rate and extent of precipitation.
Related links
Also in the Knowledge Center
Scientific Article
/ Jan 01, 1996
Preparation, crystal structure and mechanism of formation of a novel dinuclear carbopentazane complex, [Rh2(PPh3)4{(NH2NH)2CH2}][NO3]2
Read more
Scientific Article
Scientific Article