Knowledge Center

Patent / Jan 01, 1977

Polyphosphate complexes of 6-demethyl-6-deoxy-6-methylenetetracycline and its 11a-halo derivatives

Authors:
  • Ivan Villax
Source:
ES 420504

5-Hydroxytetracycline 6,12-hemiacetal 12-phosphite was dehydrated by P2O5 to give 6-deoxy-6-demethyl-6-methylene-5-hydroxytetracycline polymetaphosphate. Similarly prepd. was 11a-chloro-6-deoxy-6-demethyl-6-methylene-5-hydroxytetracycline metaphosphate.

Also in the Knowledge Center

Related Content

Continuous Tableting for Drug Product

ËÄÉ«AV´s pragmatic approach to bridging science with manufacturing is now being leveraged for continuous tableting and it is the key to ultimately providing high quality medicines and the success of your drug product.

Page
Read more

Wet Polishing

This is a proprietary ËÄÉ«AV technology for addressing complex particle reduction challenges.

Page
Read more

Dry Powder Inhalation formulation development

ËÄÉ«AV has considerable inhalation experience that allows us to implement strategies including conventional carrier based, neat (drug-alone) or composite particle formulations.

Page
Read more