Knowledge Center

Patent / Aug 18, 2016

New polymorphic forms of minocycline base and process for their preparation

Authors:
  • Zita Mendes
  • Constanca Cacela
Source:
WO 2016128760

The present invention concerns new forms of crystalline minocycline base. In particular, two new crystalline polymorphic forms, designated Form IV and Form V of minocycline base are provided. These are characterized by XRD, FTIR and TGA. Processes for preparing the new polymorphic forms and their use in pharmaceutical compositions are also provided. Form IV and form V are prepared by dissolving and/or suspending minocycline base in an organic solvent followed by crystallization.

Also in the Knowledge Center

Related Content

Sustainability

ËÄÉ«AV is committed to doing its part for a better world.

Page
Read more

ËÄÉ«AV strengthens its global position as a top employer for the third consecutive year

Press Release / Jan 16, 2025
Article
View

Process Safety

Process safety is a blend of engineering and management skills that focuses on the prevention of events impacting safety, environmental damage and business losses.

Page
Read more