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New crystalline forms of vilanterol trifenatate and processes for their preparation
The present invention relates to new cryst. forms of vilanterol trifenatate, processes for their prepn., and their use in a pharmaceutical compn. for the treatment of respiratory diseases, particularly for the treatment of asthma and chronic obstructive pulmonary disease.听 In particular, the present invention relates to a cryst. form of vilanterol trifenatate characterised in that the form has an XRPD pattern as defined herein having characteristic diffraction angles (2-theta or 2螛 (掳)) falling within or at each end of one or more of the following ranges: (a) 3 to 5掳, such as 3.8 to 4.4掳; and/or (b) 7 to 9.9掳, such as 7 to 8.5掳; and/or (c) 12 to 13.3掳, such as 12 to 13.3掳; and/or (d) 16.4 to 17.3掳, such as 16.4 to 17.3掳; and/or (e)26.8 to 28.3掳, such as 26.8 to 28.3掳.
听