Knowledge Center
Patent / Mar 12, 2013
Methods of Synthesizing Factor Xa Inhibitors
Source:
WO2011084519A1
Described herein are novel methods of preparing a compound of Formula II or a pharmaceutically acceptable salt thereof. In some embodiments, the method is for preparing betrixaban or a pharmaceutically acceptable salt thereof. Also described are compositions comprising substantially pure betrixaban free base or salt thereof.
Ìý
Also in the Knowledge Center
/ Sep 01, 2023
In vitro dissolution/permeation tools for amorphous solid dispersions bioavailability forecasting I: Experimental design for PermeaLoop
Read more
Scientific Article
/ Sep 01, 2023
In vitro dissolution/permeation tools for amorphous solid dispersions bioavailability forecasting II: Comparison and mechanistic insights
Read more
Scientific Article
Scientific Article