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Patent / Mar 12, 2013

Methods of Synthesizing Factor Xa Inhibitors

Authors:
  • Emilia Leitao
  • Jose Rato
  • Anjali Pandey
  • Jake Zhiguo Song
Source:
WO2011084519A1

Described herein are novel methods of preparing a compound of Formula II or a pharmaceutically acceptable salt thereof. In some embodiments, the method is for preparing betrixaban or a pharmaceutically acceptable salt thereof. Also described are compositions comprising substantially pure betrixaban free base or salt thereof.