Knowledge Center

Patent / Jan 01, 1974

Corticosteroid 21-sulfate and phosphate esters

Authors:
  • Ivan Villax
Source:
ZA 7203373

Betamethasone phosphate (I; R = H, R1 = OPO3H) was prepd. in 92.5% yield by treating diiodopregnadienedione I (R = R1 = iodo) with K2HPO4-H3PO4. The sulfate ester I (R = H, R1 = OSO3H) was obtained similarly.

Also in the Knowledge Center

Related Content

贰辫颈诲别濒鈩

贰辫颈诲别濒鈩 is an innovative technology with the ability to deliver sustained-release pharmaceuticals via surface erosion resulting in the ability to precisely tune pharmacokinetics to meet the target indication needs.

Page
Read more

Membrane Technology

四色AV has a wide range of membrane capabilities at its disposal including nanofiltration and ultrafiltration.

Page
Read more

Drug Substance Manufacturing

We have an exceptional range of flexible manufacturing equipment to ensure availability and suitability for our customers鈥 manufacturing needs.

Page
Read more