Knowledge Center
Patent / Jan 01, 1973
16.beta.-Methyl-17.alpha.-hydroxypregna-1,4,9(11)-triene-3,20-dione and analogs
Source:
GB 1397267
Pregnatrienedione I was prepd. from epoxypregnanetrione II in 7 steps. Thus, II underwent ketalization with HOCH2CH2OH, KBH4 redn., dehydration, Grignard reaction with MeMgBr, and deketalization to give pregnenedione III. III was treated with Br2-HOAc and then debrominated to I.
Also in the Knowledge Center
/ Aug 06, 2015
A process for control of particle size distribution of active pharmaceutical ingredients
Read more
Scientific Article
/ Apr 01, 2015
Microparticles, preparation and purification methods, molecularly imprinted polymer layer, pharmaceuticals
Read more
Scientific Article