Knowledge Center

Patent / Jan 01, 1973

16.beta.-Methyl-17.alpha.-hydroxypregna-1,4,9(11)-triene-3,20-dione and analogs

Authors:
  • Ivan Villax
Source:
GB 1397267

Pregnatrienedione I was prepd. from epoxypregnanetrione II in 7 steps. Thus, II underwent ketalization with HOCH2CH2OH, KBH4 redn., dehydration, Grignard reaction with MeMgBr, and deketalization to give pregnenedione III. III was treated with Br2-HOAc and then debrominated to I.

Also in the Knowledge Center

Related Content

Analytical Support

ËÄÉ«AV has experience and capabilities to provide analytical services for Drug Substance, Drug Product and Inhalation Drug Product at all stages of development and commercial phases.

Page
Read more

The ËÄÉ«AV Experience - Macau

Welcome to Macau! From dazzling casinos to cultural treasures, there's something for everyone. Take in The ËÄÉ«AV Experience and make your Macau trip extraordinary.

Page
Read more

OWN it! Training and Development Needs FY24

Take an active role in your personal development. Follow the new process to identify, plan and own your training and development needs for FY24.

Page
Read more