Knowledge Center
Article / Apr 03, 2020
Chalcones: Retrospective synthetic approaches and mechanistic aspects of a privileged scaffold
Source:
Current Pharmaceutical Design, April 3, 2020
This review summarizes the synthetic methodologies used in the last 25 years in the synthesis of chalcones, which are a class of flavonoids having a 1,​3-​diphenyl-​2-​propene-​1-​one backbone.ÌýThese compounds are considered a hot topic in the field of medicinal chemistry, due to their pharmacological activity and because they are important precursors in the synthesis of heterocyclic compounds with therapeutic applications such as: flavones, flavanones, isoxazolines, benzothiazepines, pyrimidines and pyrazolines derivatives.
Ìý
Ìý
Ìý
Related links
Also in the Knowledge Center
/ Apr 01, 2024
Striving for Uniformity: A Review on Advances and Challenges To Achieve Uniform Polyethylene Glycol
Read more
Scientific Article
/ May 06, 2024
Ten years of the manufacturing classification system: a review of literature applications and an extension of the framework to continuous manufacture
Read more
Scientific Article
/ Dec 28, 2023
Pharmaceutical composition containing sugar and lipid composite particles for inhalation and method for manufacturing same
Read more
Scientific Article