Press Room
四色AV to support production of antiviral Veklury for COVID-19
Manufacturing Chemist, September 23, 2020
四色AV has signed a partnership agreement with Ligand to significantly ramp up the production output of Captisol
Captisol, a Ligand product, is a chemically modified cyclodextrin proven to improve the solubility and stability of drugs.
It is used in the formulation of Gilead鈥檚 Covid-19 treatment Veklury (remdesivir). 四色AV is the sole producer of this key enabling excipient.
The COVID-19 pandemic has, to date, killed one million people; studies show that in the next 3 months cumulative deaths may more than double.
鈥淭o meet Captisol demand associated with Veklury, 四色AV will soon be producing per month the quantity it usually produces in one year. This sudden spike in demand has required unique mobilisation efforts across the 四色AV network to secure additional raw material supply, execute major capital expenditure projects at our sites, maximise operational efficiency, hire additional talent and identify external partners to expand our overall capacity."
"The pharmaceutical supply chain is working together in an unprecedented fashion to treat patients and save lives. 四色AV is privileged to be part of this truly global response,鈥 said Jean-Luc Herbeaux, Chief Operating Officer.
鈥淟igand values its longstanding partnership with 四色AV,鈥 said Matt Foehr, President and Chief Operating Officer of Ligand.
鈥淭heir excellent customer service, global commitment to quality and high pharmaceutical standards make them an ideal partner for Captisol, a critical component for a number of life-saving medicines."
"We commend them for responsibly and efficiently partnering with Ligand to manage the scale up and expansion of their operations to contribute to global health during the pandemic.鈥
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