Knowledge Center
Patent / Jan 01, 1972
9-Fluoro-16.beta.-methyl steroids
Source:
US 3792046
The title compds. (I) were prepd. from pregnatriene (II) by treatment with MeCONHBr and aq. HClO4 to give the 9.alpha.-bromo-11.beta.-hydroxy deriv., treatment with NaOH to give the 9,11-epoxy deriv. which was treated with aq. HF to give I (R = H) which could be treated with I-MeOH in the presence of CaO to give the 21-diiodo deriv. which was treated with KOAc, giving I (R = OAc).
Also in the Knowledge Center
/ Apr 01, 2024
Striving for Uniformity: A Review on Advances and Challenges To Achieve Uniform Polyethylene Glycol
Read more
Scientific Article
/ May 06, 2024
Ten years of the manufacturing classification system: a review of literature applications and an extension of the framework to continuous manufacture
Read more
Scientific Article
/ Dec 28, 2023
Pharmaceutical composition containing sugar and lipid composite particles for inhalation and method for manufacturing same
Read more
Scientific Article